Benefits of Manuka Honey for Immunity and Wound Healing

anti-inflammatory antibacterial antioxidant boosting immunity digestive health manuka honey manuka honey uses mgo natural remedy skin health umf rating well-being wound healing Apr 09, 2024

Introduction

Manuka honey, a natural wonder hailing from the pristine landscapes of New Zealand, has captured the attention of health enthusiasts and medical professionals worldwide. This unique honey, derived from the nectar of the Manuka bush (Leptospermum scoparium), boasts a host of remarkable health benefits that set it apart from other varieties. Beyond its delightful taste and luxurious texture, Manuka honey has gained global recognition for its potent antibacterial properties and its ability to enhance immunity and promote wound healing.

The secret behind Manuka honey's extraordinary properties lies in its unique composition. Unlike regular honey, Manuka honey contains significantly higher levels of methylglyoxal (MGO), a compound that gives it its distinctive antibacterial characteristics. The concentration of MGO in Manuka honey is measured using the Unique Manuka Factor (UMF) rating system, which assigns a numerical value to indicate the honey's potency. The higher the UMF rating, the more powerful the honey's antibacterial effects.

One of the most notable benefits of Manuka honey is its ability to support and strengthen the immune system. Rich in antioxidants, this honey helps combat harmful free radicals in the body, reducing oxidative stress and inflammation. By neutralizing these damaging agents, Manuka honey contributes to overall health and well-being. Moreover, the prebiotic properties of Manuka honey play a crucial role in promoting a healthy gut environment. A well-balanced gut microbiome is essential for maintaining a robust immune system, as it acts as the body's first line of defense against pathogens.

In addition to its immune-boosting qualities, Manuka honey has gained significant attention for its remarkable wound-healing properties. When applied topically to cuts, burns, or skin infections, Manuka honey creates a moist healing environment that promotes tissue regeneration and reduces the risk of infection. The natural antibacterial qualities of this honey help to ward off harmful bacteria, while its anti-inflammatory effects alleviate pain and swelling at the wound site. These unique properties make Manuka honey a valuable tool in the management and treatment of various skin conditions.

Incorporating Manuka honey into your daily routine is a simple and delicious way to reap its numerous health benefits. Whether consumed orally or applied topically, this natural remedy offers a holistic approach to supporting your immune system and promoting healing. However, it is essential to choose high-quality, authentic Manuka honey with a UMF rating of 10 or higher to ensure optimal potency and effectiveness.

In this blog post, we will delve deeper into the science behind Manuka honey's extraordinary properties and explore the various ways in which it can support your health and well-being. From its immune-enhancing effects to its wound-healing capabilities, we will uncover the secrets of this natural wonder and provide practical guidance on how to incorporate it into your daily life. Join us on this journey as we discover the remarkable benefits of Manuka honey and unlock the key to a healthier, more resilient you.

 

Section 1: The Unique Properties of Manuka Honey

Manuka honey, derived from the nectar of the Manuka bush (Leptospermum scoparium), is a unique variety that sets itself apart from other types of honey. Native to New Zealand, the Manuka bush thrives in the country's pristine and unspoiled landscapes, giving rise to a honey with unparalleled properties. The distinct characteristics of Manuka honey can be attributed to the presence of specific compounds, most notably methylglyoxal (MGO).

MGO is a naturally occurring compound that is responsible for Manuka honey's potent antibacterial effects. While all types of honey possess some level of antibacterial activity due to the presence of hydrogen peroxide, Manuka honey stands out due to its high concentration of MGO. This unique compound is formed through a chemical reaction between dihydroxyacetone, found in the nectar of the Manuka flower, and other naturally occurring substances in the honey.

To quantify the antibacterial strength of Manuka honey, the Unique Manuka Factor (UMF) rating system was developed. The UMF rating is a standardized measure that indicates the concentration of MGO and other beneficial compounds in the honey. The higher the UMF rating, the more potent the antibacterial properties of the Manuka honey. Ratings range from UMF 5+ to UMF 20+, with higher ratings indicating superior quality and efficacy.

In addition to MGO, Manuka honey also contains other beneficial compounds that contribute to its unique properties. These include phenolic acids, flavonoids, and other antioxidants that work synergistically to enhance the honey's health benefits. These compounds help to neutralize harmful free radicals in the body, reducing oxidative stress and inflammation, which are key factors in many chronic health conditions.

The combination of MGO and other beneficial compounds in Manuka honey creates a powerful natural remedy with a wide range of applications. From supporting immune function to promoting wound healing, the unique properties of Manuka honey have been recognized and utilized for centuries by the indigenous Mฤori people of New Zealand. Today, scientific research continues to uncover the mechanisms behind Manuka honey's remarkable effects, validating its use as a natural and effective health supplement.

When selecting Manuka honey, it is crucial to choose a high-quality product with a verified UMF rating. Look for honey that has been tested and certified by independent laboratories to ensure its authenticity and potency. By opting for genuine, high-grade Manuka honey, you can be confident that you are harnessing the full potential of this natural wonder and maximizing its benefits for your health and well-being.

Section 2: Manuka Honey and Immunity

One of the most significant benefits of Manuka honey lies in its ability to support and enhance immune function. A strong and resilient immune system is essential for protecting the body against harmful pathogens, preventing illness, and promoting overall health. Manuka honey's unique properties make it a valuable ally in boosting immunity, thanks to its high antioxidant content and prebiotic effects.

Antioxidants play a crucial role in maintaining a healthy immune system. These powerful compounds help to neutralize harmful free radicals, which are unstable molecules that can damage cells and contribute to oxidative stress and inflammation. Manuka honey is particularly rich in antioxidants, including phenolic acids and flavonoids, which work together to combat oxidative damage and support immune function.

Research has shown that the antioxidants found in Manuka honey can help to stimulate the production of immune cells, such as lymphocytes and phagocytes, which are essential for defending the body against invading pathogens. By enhancing the activity of these immune cells, Manuka honey helps to strengthen the body's natural defense mechanisms, making it more effective at fighting off infections and diseases.

In addition to its antioxidant content, Manuka honey also exhibits prebiotic properties that contribute to immune health. Prebiotics are non-digestible compounds that serve as food for the beneficial bacteria in the gut, known as probiotics. A healthy balance of gut bacteria is crucial for maintaining a strong immune system, as the gut is home to approximately 70% of the body's immune cells.

Manuka honey contains specific prebiotic compounds, such as oligosaccharides, that selectively stimulate the growth and activity of beneficial gut bacteria. By promoting the growth of these health-promoting microbes, Manuka honey helps to create a favorable environment in the gut, which in turn supports immune function. A well-balanced gut microbiome is essential for optimal nutrient absorption, immune regulation, and overall health.

Several studies have demonstrated the immune-enhancing effects of Manuka honey. For example, a study published in the journal Food and Chemical Toxicology found that consuming Manuka honey increased the production of antibodies and stimulated the activity of immune cells in mice. Another study, published in the journal PLOS ONE, showed that Manuka honey reduced inflammation and oxidative stress in human cell cultures, further highlighting its potential to support immune health.

To maximize the immune-boosting benefits of Manuka honey, it is recommended to consume it regularly, either on its own or as part of a balanced diet. A daily dose of one to two tablespoons of high-quality Manuka honey can help to support immune function and promote overall health. Additionally, incorporating Manuka honey into a healthy lifestyle that includes a nutrient-rich diet, regular exercise, and stress management techniques can further enhance its immune-supporting effects. 

Section 3: Wound Healing Properties of Manuka Honey

One of the most remarkable properties of Manuka honey is its ability to promote wound healing and prevent infection. For centuries, honey has been used as a natural remedy for treating wounds, burns, and skin infections, and Manuka honey has proven to be particularly effective in this regard. The unique antibacterial and anti-inflammatory properties of Manuka honey make it an ideal topical treatment for a wide range of skin conditions.

Manuka honey's potent antibacterial activity is largely attributed to its high concentration of methylglyoxal (MGO). This compound has been shown to effectively inhibit the growth of a wide range of bacteria, including antibiotic-resistant strains such as Methicillin-resistant Staphylococcus aureus (MRSA). By creating an inhospitable environment for harmful bacteria, Manuka honey helps to prevent infection and promote healing.

In addition to its antibacterial properties, Manuka honey also possesses remarkable wound-healing capabilities. When applied topically to a wound, Manuka honey creates a moist, protective barrier that promotes the healing process. This moist environment prevents the wound from drying out and becoming prone to further damage or infection. The honey's high sugar content and low pH level also contribute to its ability to draw fluid away from the wound, reducing inflammation and swelling.

Manuka honey's anti-inflammatory properties play a crucial role in the wound-healing process. Inflammation is a natural response to injury, but excessive or prolonged inflammation can hinder healing and cause additional damage to the surrounding tissue. The unique compounds found in Manuka honey, such as phenolic acids and flavonoids, help to reduce inflammation by modulating the body's immune response. This not only alleviates pain and discomfort but also accelerates the healing process.

Numerous studies have demonstrated the effectiveness of Manuka honey in promoting wound healing. A systematic review published in the journal BMC Complementary and Alternative Medicine found that Manuka honey significantly reduced healing time and improved outcomes in patients with various types of wounds, including burns, surgical wounds, and diabetic ulcers. Another study, published in the journal PLOS ONE, showed that Manuka honey effectively reduced inflammation and promoted tissue regeneration in an animal model of wound healing.

To harness the wound-healing benefits of Manuka honey, it can be applied topically to the affected area. It is essential to choose a high-quality, medical-grade Manuka honey product with a UMF rating of 10 or higher to ensure optimal effectiveness. Applying a thin layer of Manuka honey to the wound and covering it with a sterile dressing can help to promote healing and prevent infection. As with any wound care regimen, it is essential to consult with a healthcare professional for proper guidance and to monitor the healing process closely.

Section 4: How to Incorporate Manuka Honey into Your Daily Routine

Incorporating Manuka honey into your daily routine is a simple and effective way to support your immune system and promote overall health. There are several ways to enjoy the benefits of Manuka honey, whether consumed orally or applied topically.

One of the most common ways to consume Manuka honey is by taking it orally. A daily dose of one to two tablespoons of high-quality Manuka honey can help to support immune function and provide a natural energy boost. Manuka honey can be consumed on its own, stirred into warm water or tea, or added to smoothies or other beverages. It is important to note that heating Manuka honey to high temperatures can diminish its beneficial properties, so it is best to add it to warm, rather than boiling, liquids.

Manuka honey can also be incorporated into your diet by using it as a natural sweetener in recipes. Its unique flavor profile and health benefits make it an excellent substitute for refined sugars in baked goods, sauces, and dressings. When cooking with Manuka honey, it is essential to keep the temperature below 40°C (104°F) to preserve its beneficial compounds.

For topical application, Manuka honey can be used as a natural remedy for minor wounds, burns, and skin infections. To use Manuka honey for wound care, first, ensure that the wound is clean and free of debris. Apply a thin layer of high-quality, medical-grade Manuka honey directly to the affected area and cover it with a sterile dressing. Change the dressing and reapply the honey daily, or as directed by a healthcare professional.

When selecting Manuka honey for oral consumption or topical application, it is crucial to choose a product with a UMF rating of 10 or higher. This rating ensures that the honey has a significant level of antibacterial activity and contains the beneficial compounds that contribute to its health benefits. It is also essential to choose a reputable brand that follows strict quality control standards and provides transparent information about the honey's origin and testing results.

While Manuka honey is generally safe for most people, there are a few precautions to keep in mind. People with allergies to bees or bee products should exercise caution when consuming Manuka honey. Additionally, infants under the age of one should not consume any type of honey, including Manuka honey, due to the risk of botulism.

Incorporating Manuka honey into your daily routine is a simple and delicious way to support your immune system, promote wound healing, and enhance overall health. By selecting a high-quality product and consuming it regularly, you can enjoy the numerous benefits of this natural wonder. As with any dietary supplement or natural remedy, it is always best to consult with a healthcare professional to determine the most appropriate use for your individual needs and health status. 

Section 5: Additional Benefits of Manuka Honey

Beyond its well-known benefits for immunity and wound healing, Manuka honey has been associated with a wide range of other potential health advantages. These additional benefits make Manuka honey a versatile and valuable natural remedy for supporting overall health and well-being.

One of the most promising areas of research involves Manuka honey's potential benefits for digestive health. The prebiotic properties of Manuka honey, as discussed earlier, can help to promote the growth of beneficial gut bacteria, which are essential for maintaining a healthy digestive system. A well-balanced gut microbiome is crucial for proper nutrient absorption, regular bowel movements, and the prevention of digestive disorders such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Moreover, the antibacterial properties of Manuka honey may help to combat harmful bacteria in the gut, such as Helicobacter pylori, which is associated with the development of stomach ulcers and gastritis. A study published in the journal PLOS ONE found that Manuka honey effectively inhibited the growth of H. pylori and suggested that it could be used as a complementary treatment for these digestive conditions.

Manuka honey has also been traditionally used to soothe sore throats and support respiratory health. Its natural antibacterial and anti-inflammatory properties can help to alleviate the discomfort associated with throat infections and reduce inflammation in the respiratory tract. Consuming Manuka honey, either on its own or mixed with warm water or tea, may provide relief from coughs, colds, and other respiratory ailments.

In addition to its internal health benefits, Manuka honey has gained popularity in the skincare industry due to its potential to promote healthy, glowing skin. The antibacterial and anti-inflammatory properties of Manuka honey make it an effective natural treatment for acne, as it can help to reduce the severity and frequency of breakouts. Manuka honey's ability to promote wound healing also extends to the skin, as it can help to soothe and repair damaged or irritated skin, such as in the case of eczema or psoriasis.

Furthermore, the antioxidants found in Manuka honey can help to protect the skin from oxidative stress and premature aging. By neutralizing harmful free radicals, these antioxidants may help to reduce the appearance of fine lines, wrinkles, and age spots, promoting a more youthful and radiant complexion.

While more research is needed to fully understand the extent of Manuka honey's additional health benefits, the existing evidence suggests that this natural wonder has much to offer beyond its well-established effects on immunity and wound healing. By incorporating Manuka honey into your daily routine, you may be able to support your digestive health, respiratory function, and skin health, all while enjoying its delicious, natural sweetness.

Section 6: Choosing the Best Manuka Honey

With the growing popularity of Manuka honey, the market has become flooded with a wide variety of products, making it crucial to know how to choose the best Manuka honey to ensure that you are getting a high-quality, authentic product that will provide the desired health benefits.

One of the most important factors to consider when selecting Manuka honey is the Unique Manuka Factor (UMF) rating. As discussed earlier, the UMF rating is a standardized measure of the honey's antibacterial activity, which is directly related to its concentration of methylglyoxal (MGO). When choosing Manuka honey, opt for products with a UMF rating of 10 or higher to ensure that you are getting a potent, effective product.

In addition to the UMF rating, there are other certifications and labels to look for when purchasing Manuka honey. The MGO content, which is directly responsible for the honey's antibacterial properties, may also be listed on the label. Some brands may use the term "Active Manuka Honey" or "Non-Peroxide Activity" (NPA) to indicate that the honey has significant antibacterial activity.

It is also essential to ensure that the Manuka honey you choose is authentic and pure. Look for products that are labeled as "Raw" or "Unpasteurized," as the pasteurization process can destroy some of the honey's beneficial compounds. Additionally, choose Manuka honey that is sourced directly from New Zealand, as this is the only place where genuine Manuka honey is produced.

To further guarantee the authenticity and quality of your Manuka honey, purchase from reputable brands and suppliers that are transparent about their sourcing and testing methods. Some of the most well-known and trusted Manuka honey brands include Comvita, Manuka Health, and Wedderspoon. These companies often provide detailed information about the origin of their honey, as well as the testing methods used to verify its purity and potency.

When storing Manuka honey, it is important to keep it in a cool, dark place, away from direct sunlight and heat sources. Proper storage helps to preserve the honey's beneficial properties and extend its shelf life. Manuka honey can be stored at room temperature and will generally remain stable for several years, although some crystallization may occur over time. If crystallization does occur, the honey can be gently warmed to restore its liquid consistency.

In conclusion, choosing the best Manuka honey involves looking for high UMF ratings, authentic labeling, and reputable brands. By taking the time to select a high-quality, pure Manuka honey, you can ensure that you are getting the full range of health benefits that this natural wonder has to offer. Whether you are looking to support your immune system, promote wound healing, or simply enjoy the delicious taste of this unique honey, investing in a premium Manuka honey product is a smart choice for your health and well-being. 

Conclusion

In conclusion, Manuka honey is a truly remarkable natural remedy with a wide range of health benefits. Its unique antibacterial properties, derived from its high concentration of methylglyoxal (MGO), make it a powerful ally in supporting immune function and promoting wound healing. The Unique Manuka Factor (UMF) rating system provides a standardized measure of the honey's potency, ensuring that consumers can choose high-quality, effective products.

Beyond its well-known benefits for immunity and wound healing, Manuka honey has shown promise in supporting digestive health, respiratory function, and skin health. Its prebiotic properties help to promote a healthy gut microbiome, while its antibacterial and anti-inflammatory effects may offer relief from digestive disorders, sore throats, and skin conditions such as acne and eczema.

The antioxidants found in Manuka honey further contribute to its health benefits, helping to neutralize harmful free radicals and protect the body from oxidative stress and inflammation. These antioxidants also offer potential benefits for skin health, promoting a more youthful and radiant complexion.

Incorporating Manuka honey into your daily routine is a simple and delicious way to support your overall health and well-being. Whether consumed orally or applied topically, this natural wonder offers a wide range of potential benefits, backed by scientific research and traditional wisdom.

When selecting Manuka honey, it is crucial to choose a high-quality, authentic product with a UMF rating of 10 or higher. By purchasing from reputable brands and suppliers that prioritize transparency and purity, you can ensure that you are getting the full range of health benefits that Manuka honey has to offer.

As with any natural remedy, it is essential to use Manuka honey responsibly and in moderation. While it is generally safe for most people, those with allergies to bees or bee products should exercise caution, and infants under the age of one should not consume honey due to the risk of botulism.

In summary, Manuka honey is a powerful natural remedy with a wide range of potential health benefits. By incorporating this unique and versatile honey into your daily routine, you can support your immune system, promote wound healing, and enjoy a range of other potential benefits for your digestive health, respiratory function, and skin health. With its delicious taste and proven efficacy, Manuka honey is truly a gift from nature that can help to support and enhance your overall health and well-being.

Action Steps

  1. Educate yourself about Manuka honey: Take the time to learn about the unique properties and potential health benefits of Manuka honey. Read reputable sources, such as scientific journals and trusted health websites, to gain a deeper understanding of how this natural remedy can support your health and well-being.
  2. Choose a high-quality Manuka honey: When purchasing Manuka honey, look for products with a UMF rating of 10 or higher to ensure that you are getting a potent and effective product. Choose raw, unpasteurized honey from reputable brands that are transparent about their sourcing and testing methods.
  3. Incorporate Manuka honey into your diet: Start by adding one to two tablespoons of Manuka honey to your daily routine. You can consume it on its own, stir it into warm water or tea, or add it to smoothies and other beverages. Remember to keep the temperature below 40°C (104°F) to preserve the honey's beneficial properties.
  4. Use Manuka honey for wound care: If you have a minor wound, burn, or skin infection, consider using Manuka honey as a natural treatment. Clean the affected area, apply a thin layer of high-quality, medical-grade Manuka honey, and cover it with a sterile dressing. Change the dressing and reapply honey daily, or as directed by a healthcare professional.
  5. Experiment with Manuka honey in recipes: Try using Manuka honey as a natural sweetener in your favorite recipes. Its unique flavor profile and health benefits make it an excellent substitute for refined sugars in baked goods, sauces, and dressings. Remember to keep the temperature low to preserve the honey's beneficial compounds.
  6. Share your knowledge with others: Spread the word about the potential health benefits of Manuka honey with friends, family, and colleagues. Share articles, recipes, and personal experiences to help others learn about this natural wonder and how it can support their health and well-being.
  7. Consult with a healthcare professional: If you have any pre-existing health conditions or concerns, consult with a healthcare professional before incorporating Manuka honey into your daily routine. They can provide personalized guidance and help you determine the best way to use this natural remedy to support your unique health needs.
  8. Monitor your progress: Keep track of your health and well-being as you incorporate Manuka honey into your daily routine. Take note of any improvements in your immune function, wound healing, digestive health, respiratory function, or skin health, and adjust your usage accordingly.

By following these action steps, you can harness the power of Manuka honey to support your health and well-being. Remember to use this natural remedy responsibly, choose high-quality products, and consult with a healthcare professional if you have any concerns. With consistent use and a commitment to a healthy lifestyle, Manuka honey can be a valuable addition to your natural health toolkit. 

Further Reading

Health Sites and Websites:

  1. WebMD - Manuka Honey: Benefits, Uses, and More (https://www.webmd.com/diet/manuka-honey-benefits-uses)
  2. Healthline - 7 Proven Benefits of Manuka Honey (https://www.healthline.com/nutrition/manuka-honey-benefits)
  3. Medical News Today - What are the benefits of Manuka honey? (https://www.medicalnewstoday.com/articles/264667)

Medical Organizations:

  1. National Center for Complementary and Integrative Health (NCCIH) - Honey (https://www.nccih.nih.gov/health/honey)
  2. American Apitherapy Society - Manuka Honey (https://www.apitherapy.org/manuka-honey/)

Universities:

  1. University of Waikato - Honey Research Unit (https://www.waikato.ac.nz/honey-research/)
  2. University of Sydney - Honey Research Laboratory (https://www.sydney.edu.au/science/our-research/research-areas/life-and-environmental-sciences/honey-research-laboratory.html)

Peer-Reviewed Articles:

  1. Carter, D. A., Blair, S. E., Cokcetin, N. N., Bouzo, D., Brooks, P., Schothauer, R., & Harry, E. J. (2016). Therapeutic Manuka Honey: No Longer So Alternative. Frontiers in Microbiology, 7, 569. (https://doi.org/10.3389/fmicb.2016.00569)
  2. Mavric, E., Wittmann, S., Barth, G., & Henle, T. (2008). Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand. Molecular Nutrition & Food Research, 52(4), 483-489. (https://doi.org/10.1002/mnfr.200700282)
  3. Mandal, M. D., & Mandal, S. (2011). Honey: its medicinal property and antibacterial activity. Asian Pacific Journal of Tropical Biomedicine, 1(2), 154-160. (https://doi.org/10.1016/S2221-1691(11)60016-6)
  4. Tomblin, V., Ferguson, L. R., Han, D. Y., Murray, P., & Schlothauer, R. (2014). Potential pathway of anti-inflammatory effect by New Zealand honeys. International Journal of General Medicine, 7, 149-158. (https://doi.org/10.2147/IJGM.S45839)
  5. Niaz, K., Maqbool, F., Bahadar, H., & Abdollahi, M. (2017). Health Benefits of Manuka Honey as an Essential Constituent for Tissue Regeneration. Current Drug Metabolism, 18(10), 881-892. (https://doi.org/10.2174/1389200218666170911152240)
  6. Almasaudi, S. B., El-Shitany, N. A., Abbas, A. T., Abdel-dayem, U. A., Ali, S. S., Al Jaouni, S. K., & Harakeh, S. (2016). Antioxidant, Anti-inflammatory, and Antiulcer Potential of Manuka Honey against Gastric Ulcer in Rats. Oxidative Medicine and Cellular Longevity, 2016, 3643824. (https://doi.org/10.1155/2016/3643824)
  7. Oryan, A., Alemzadeh, E., & Moshiri, A. (2016). Biological properties and therapeutic activities of honey in wound healing: A narrative review and meta-analysis. Journal of Tissue Viability, 25(2), 98-118. (https://doi.org/10.1016/j.jtv.2015.12.002)
  8. Schencke, C., Salvo, J., Vasconcellos, A., & del Sol, M. (2013). Antimicrobial activity of Manuka honey on pathogenic bacteria isolated from human wounds. International Journal of Morphology, 31(3), 1036-1041. (https://doi.org/10.4067/S0717-95022013000300040)
  9. Al-Waili, N., Salom, K., & Al-Ghamdi, A. A. (2011). Honey for wound healing, ulcers, and burns; data supporting its use in clinical practice. TheScientificWorldJournal, 11, 766-787. (https://doi.org/10.1100/tsw.2011.78)
  10. Gethin, G. T., Cowman, S., & Conroy, R. M. (2008). The impact of Manuka honey dressings on the surface pH of chronic wounds. International Wound Journal, 5(2), 185-194. (https://doi.org/10.1111/j.1742-481X.2007.00424.x)
  11. Acevedo, F., Torres, P., Oomah, B. D., de Alencar, S. M., Massarioli, A. P., Martín-Venegas, R., Albarral-Ávila, V., Burgos-Díaz, C., Ferrer, R., & Rubilar, M. (2017). Volatile and non-volatile/semi-volatile compounds and in vitro bioactive properties of Chilean Ulmo (Eucryphia cordifolia Cav.) honey. Food Research International, 94, 20-28. (https://doi.org/10.1016/j.foodres.2017.01.021)
  12. Kwakman, P. H., te Velde, A. A., de Boer, L., Vandenbroucke-Grauls, C. M., & Zaat, S. A. (2011). Two major medicinal honeys have different mechanisms of bactericidal activity. PloS one, 6(3), e17709. (https://doi.org/10.1371/journal.pone.0017709)
  13. Alandejani, T., Marsan, J., Ferris, W., Slinger, R., & Chan, F. (2009). Effectiveness of honey on Staphylococcus aureus and Pseudomonas aeruginosa biofilms. Otolaryngology--Head and Neck Surgery, 141(1), 114-118. (https://doi.org/10.1016/j.otohns.2009.01.005)
  14. Lu, J., Turnbull, L., Burke, C. M., Liu, M., Carter, D. A., Schlothauer, R. C., Whitchurch, C. B., & Harry, E. J. (2014). Manuka-type honeys can eradicate biofilms produced by Staphylococcus aureus strains with different biofilm-forming abilities. PeerJ, 2, e326. (https://doi.org/10.7717/peerj.326)
  15. Sherlock, O., Dolan, A., Athman, R., Power, A., Gethin, G., Cowman, S., & Humphreys, H. (2010). Comparison of the antimicrobial activity of Ulmo honey from Chile and Manuka honey against methicillin-resistant Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. BMC Complementary and Alternative Medicine, 10, 47. (https://doi.org/10.1186/1472-6882-10-47)

These resources provide a comprehensive overview of the current research and knowledge on Manuka honey's health benefits, particularly in the areas of wound healing and antibacterial properties. The peer-reviewed articles offer in-depth, scientific evidence to support the claims made about Manuka honey's efficacy in various medical applications.

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